Antimicrobial Effects of Drugs against Multidrug-Resistant Pseudomonas aeruginosa

In vitro activity of antimicrobial combinations against multidrug-resistant Pseudomonas aeruginosa.

INTRODUCTION Pseudomonas aeruginosa isolates related to nosocomial infections are often resistant to multiple antibacterial agents. In this study, antimicrobial combinations were evaluated to detect in vitro synergy against clinical isolates of P. aeruginosa. METHODS Four clinical P. aeruginosa isolates were selected at random among other isolates from inpatients treated at the public Univers...

In vitro effects of combinations of antipseudomonal agents against seven strains of multidrug-resistant Pseudomonas aeruginosa.

OBJECTIVES The aim of this study was to evaluate the combined effects of antibiotic combinations by agar incorporation inhibitory tests and by time-kill tests on seven geographically and epidemiologically distinct isolates of multidrug-resistant Pseudomonas aeruginosa. All seven strains were resistant to piperacillin, meropenem, ceftazidime, cefoperazone-sulbactam, aztreonam, amikacin and cipro...

In vitro combination effects of aztreonam and aminoglycoside against multidrug-resistant Pseudomonas aeruginosa in Japan.

The aim of this study was to evaluate the in vitro combination effects of aztreonam (AZT) and aminoglycosides against multidrug-resistant (MDR) Pseudomonas aeruginosa strains in Japan. We investigated 47 MDR P. aeruginosa strains collected from 8 facilities. We selected the aminoglycosides amikacin (AMK), gentamicin (GM), and arbekacin (ABK) to examine their effects when combined with AZT u...

Antimicrobial susceptibility of imipenem-resistant Pseudomonas aeruginosa.

Dissemination of Class 1 Integron among Different Multidrug Resistant Pseudomonas aeruginosa Strains

ABSTRACT             Background and objectives: The present study was conducted to detect class 1 integrons and evaluate antibiotic susceptibility patterns among clinical isolates of P. aeruginosa.             Methods: Sixty clinical samples from blood, tracheal wounds, burns and uri...